Company Filing History:
Years Active: 2005
Title: Nancy Guzzo-Pernell: Innovator in Antisense Oligonucleotide Delivery
Introduction
Nancy Guzzo-Pernell is a distinguished inventor based in Melbourne, Australia. She has made significant contributions to the field of biotechnology, particularly in the development of peptides that facilitate the delivery of antisense oligonucleotides into cells. Her innovative work aims to enhance the efficacy of therapeutic agents in combating diseases.
Latest Patents
Nancy holds a patent for her invention titled "Peptides that deliver antisense oligonucleotides which downregulate protein expression in cells." This patent describes a peptide capable of forming a complex with an oligonucleotide, such as an antisense oligonucleotide, to effectively deliver it into a cell. The invention also encompasses compositions that include this peptide-oligonucleotide complex, methods for delivering oligonucleotides into cells, and strategies for inhibiting protein expression. Additionally, her work outlines a method for sensitizing cells to anti-cancer agents like paclitaxel, along with relevant pharmaceutical compositions. Nancy has 1 patent to her name.
Career Highlights
Nancy is affiliated with Columbia University, where she continues her research and development efforts. Her work has garnered attention for its potential applications in cancer treatment and other therapeutic areas.
Collaborations
Throughout her career, Nancy has collaborated with notable colleagues, including Cy Aaron Stein and Luba Benimetskaya. These partnerships have contributed to the advancement of her research and the successful development of her inventions.
Conclusion
Nancy Guzzo-Pernell is a pioneering inventor whose work in peptide delivery systems holds promise for improving therapeutic outcomes in various medical fields. Her contributions to biotechnology exemplify the impact of innovative research on healthcare advancements.