Nam T Vu

Title: Innovations of Nam T Vu in Microfluidic Technology

Introduction

Nam T Vu is an accomplished inventor based in Redondo Beach, California. He has made significant contributions to the field of microfluidics, particularly in the development of platforms for small sample analysis. His work has implications for biomedical research and diagnostics.

Latest Patents

Nam T Vu holds a patent for an "Integrated microfluidic radioassay and imaging platform for small sample analysis." This innovative platform utilizes an immunocapture-based in vitro kinase assay on a polydimethylsiloxane (PDMS) microfluidics platform. It is capable of reproducibly measuring kinase activity from as few as 3,000 cells. The platform employs a standard radiometric P-ATP labeled phosphate transfer assay, which required the development of methods for repeated trapping and mixing of solid-phase affinity microbeads. A solid-state beta-particle camera embedded directly below the microfluidic device enables real-time quantitative detection of signals from this and other microfluidic radio bioassays. This integrated device can measure ABL protein kinase activity from BCR-ABL positive leukemia patient samples and assess small molecule phosphorylation, such as the phosphorylation of the deoxycytidine analog F-FAC by deoxycytidine kinase (dCK) isolated from cell lysates.

Career Highlights

Nam T Vu's career is marked by his innovative approach to microfluidic technology. His work has not only advanced the field but has also provided valuable tools for researchers in the biomedical sector. His patent reflects a deep understanding of both engineering and biological principles, showcasing his ability to bridge these disciplines effectively.

Collaborations

Nam T Vu has collaborated with notable colleagues, including Thomas G Graeber and Hsian-Rong Tseng. These collaborations have likely enriched his research and contributed to the success of his innovative projects.

Conclusion

Nam T Vu's contributions to microfluidic technology exemplify the intersection of engineering and biology, paving the way for advancements in small sample analysis and biomedical research. His patent highlights the potential for innovative solutions in the field, demonstrating the importance of continued research and development in this area.