Location History:
- Okayama, JP (2007)
- Hyogo, JP (2014)
Company Filing History:
Years Active: 2007-2014
Title: Nagahide Matsubara: Innovator in Gene Amplification Technologies
Introduction
Nagahide Matsubara is a prominent inventor based in Hyogo, Japan. He has made significant contributions to the field of gene amplification, particularly in methods that can detect and analyze methylated and unmethylated nucleic acids. With a total of 2 patents, his work has implications for biological research and medical diagnostics.
Latest Patents
Matsubara's latest patents include an "Amplification method of methylated or unmethylated nucleic acid." This invention provides a gene amplification method capable of amplifying both types of nucleic acids present in biological samples. The method allows for the regulation of the amplification ratio of methylated and/or unmethylated nucleic acids as needed. It utilizes a nonspecific primer that can hybridize with both methylated and unmethylated nucleic acids, along with a specific primer that targets either type. This innovative approach enables researchers to adjust the amplification ratio by changing the mixing rate of these primers.
Another notable patent is the "Oligonucleotide-immobilized substrate for detecting methylation." This invention detects the presence or absence of methylation in CpG dinucleotides within sample DNA. It employs multiple capture oligonucleotides immobilized on a base material, which hybridize with the sample DNA. The detection process is based on the hybridization results, allowing for a clear understanding of methylation status.
Career Highlights
Throughout his career, Matsubara has worked with various companies, including Bio-Dixam, LLC and Nisshinbo Industries, Inc. His experience in these organizations has contributed to his expertise in the field of genetic research and innovation.
Collaborations
Matsubara has collaborated with notable colleagues such as Takeshi Nagasaka and Hiromi Sasamoto. These partnerships have likely enhanced his research capabilities and broadened the impact of his inventions.
Conclusion
Nagahide Matsubara's contributions to gene amplification technologies demonstrate his innovative spirit and dedication to advancing scientific research. His patents reflect a deep understanding of molecular biology and its applications in diagnostics.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.