Company Filing History:
Years Active: 1994-2000
Title: Naeem B Hanna: Innovator in Nucleotide Sequencing Technologies
Introduction
Naeem B Hanna is a prominent inventor based in Fullerton, California, known for his significant contributions to the field of nucleotide sequencing. With a total of eight patents to his name, Hanna has developed innovative methods and compounds that enhance the efficiency of labeling and sequencing processes.
Latest Patents
Hanna's latest patents include "Efficient activated cyanine dyes - Activating groups based on N-hydroxynaphthalimide." This invention discloses activating groups that mediate the coupling of labeling moieties, such as biotin or cyanine dyes, to various components, including chain terminators, nucleoside triphosphates, and oligonucleotides. These components are essential in nucleotide sequencing. The activated esters derived from these groups can react with derivatized nucleotide chain terminators to produce labeled components. Additionally, Hanna's methods allow for the labeling of nucleoside triphosphates in organic media, achieving much higher yields compared to prior art.
Another notable patent is for "2'-OMe C.sup.AC phosphoramidite and methods for preparation and use." This invention involves a compound that facilitates the synthesis of 2'-OMe RNA sequences. It introduces a reagent comprising methylamine, which enables fast cleavage and deprotection of oligonucleotides, replacing the traditional ammonium hydroxide reagent.
Career Highlights
Throughout his career, Naeem B Hanna has worked with reputable companies such as Beckman Instruments, Inc. and Beckman Coulter, Inc. His experience in these organizations has contributed to his expertise in the field of biotechnology and nucleotide sequencing.
Collaborations
Hanna has collaborated with notable colleagues, including Firdous Farooqui and Parameswara Meda Reddy. These collaborations have likely enriched his research and development efforts, leading to innovative solutions in his field.
Conclusion
Naeem B Hanna's work in nucleotide sequencing technologies showcases his innovative spirit and dedication to advancing scientific knowledge. His patents reflect a commitment to improving the efficiency and effectiveness of sequencing methods, making significant contributions to the field.