Nadege Pfender

Title: The Innovations of Nadege Pfender: A Pioneer in RNA Interference

Introduction

Nadege Pfender is an accomplished inventor based in Lispheim, France, recognized for her groundbreaking work in the field of RNA interference. With one notable patent to her name, she has made significant contributions to the scientific community, particularly in the synthesis and use of cationic siRNAs.

Latest Patents

Nadege Pfender holds a patent titled "Cationic siRNAs, synthesis and use for RNA interference." This invention relates to cationic small interfering RNAs (siRNAs) characterized by double-stranded RNA fragments, which are grafted at their ends with oligocations. The innovation is distinctive for ensuring that the number of cationic charges grafted is comparable to or greater than the anionic charges carried by the internucleoside phosphates of the RNA strands. This development opens new avenues for applications in gene silencing and therapeutic interventions.

Career Highlights

Throughout her career, Nadege Pfender has been associated with prestigious institutions, including the Centre National de la Recherche Scientifique (CNRS) and the University of Strasbourg. Her work has not only advanced scientific knowledge but also demonstrated her commitment to research and innovation in the field of molecular biology.

Collaborations

Nadege has had the privilege to collaborate with esteemed colleagues such as Jean-Paul Behr and Mitsuharu Kotera. These collaborations have enriched her research and contributed to the success of her endeavors in RNA technology.

Conclusion

Nadege Pfender exemplifies the spirit of innovation with her contributions to RNA interference through her patent on cationic siRNAs. Her academic and collaborative achievements underline her role as a vital inventor, advancing the frontiers of genetic research. Through her work, she continues to inspire future generations in the field of molecular biology and beyond.