This inventor holds 1 USPTO granted patent and 1 published patent application. Top assignee: Tianjin University of Science and Technology. Active years: 2022.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2022
Title: Innovations in Antitumor Drug Delivery by Na Guo
Introduction
Na Guo is an accomplished inventor based in Tianjin, China. She has made significant contributions to the field of antitumor drug delivery systems. Her innovative work focuses on enhancing the efficacy and targeting of antitumor drugs, which is crucial for improving cancer treatment outcomes.
Latest Patents
Na Guo holds a patent for a "Ternary conjugate of antitumor drug, and synthesis and application." This patent discloses a targeted delivery system for a hydrophobic antitumor drug. The system involves conjugates of E-selectin polypeptide ligand, polyethylene glycol, and the antitumor drug, connected by different link bridges containing disulfide bonds. The patent details the synthesis of these conjugates, evaluation of their antitumor activity, and the characteristics of nanoparticles self-assembled from the conjugates in an aqueous solution. The conjugates are designed to actively target tumor sites through the E-selectin peptide ligand and can self-assemble into nanoparticles, allowing for passive targeting via the enhanced permeability and retention (EPR) effect. The results indicate that these conjugates exhibit significant antitumor activity while being less toxic to normal cells, thus holding promise for the development of effective antitumor drugs.
Career Highlights
Na Guo is affiliated with Tianjin University of Science and Technology, where she conducts her research and development work. Her innovative approach to drug delivery systems has positioned her as a key figure in the field of cancer research.
Collaborations
Na Guo collaborates with notable colleagues, including Peng Yu and Dong Wang, who contribute to her research endeavors.
Conclusion
Na Guo's work in developing targeted delivery systems for antitumor drugs represents a significant advancement in cancer treatment. Her innovative approaches and patented technologies have the potential to improve patient outcomes and reduce side effects associated with traditional cancer therapies.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile