Company Filing History:
Years Active: 2021-2025
Title: Mykhaylo Demydchuk: Innovator in Molecular Medicine
Introduction
Mykhaylo Demydchuk is a prominent inventor based in Cambridge, GB. He has made significant contributions to the field of molecular medicine, particularly in the development of innovative polypeptides and methods for targeted delivery of therapeutic agents. With a total of 3 patents to his name, Demydchuk is recognized for his groundbreaking work that addresses critical challenges in medical treatment.
Latest Patents
Demydchuk's latest patents include the development of Type-II VNAR polypeptides that bind human transferrin receptor 1 (TfR-1). This invention focuses on high-affinity VNAR polypeptides that are cross-reactive with primate transferrin receptors. The polypeptides were obtained through screening semisynthetic VNAR phage display libraries against recombinant human TfR-1. These VNAR polypeptides can be utilized alone or as components in conjugates targeting the transferrin/transferrin receptor transport system. Furthermore, the invention encompasses the use of these VNARs and their derivatives in diagnostic and therapeutic methods, particularly for delivering biomolecules across the blood-brain barrier and other biological barriers.
Another notable patent involves in vivo methods for selecting peptides that can cross the blood-brain barrier. This invention relates to identifying membrane receptors or transporters capable of delivering therapeutic or diagnostic agents specifically to the parenchymal tissue of the brain. The methods developed by Demydchuk enhance the targeted delivery of treatments for various conditions, including cancer.
Career Highlights
Demydchuk is currently associated with Ossianix, Inc., where he continues to advance his research in molecular medicine. His work has positioned him as a key figure in the development of innovative therapeutic solutions that address complex medical challenges.
Collaborations
Demydchuk collaborates with notable colleagues, including Pawel Stocki and Krzysztof Bartlomiej Wicher. These partnerships enhance the research and development efforts at Ossianix, Inc., contributing to the advancement of their innovative projects.
Conclusion
Mykhaylo Demydchuk is a distinguished inventor whose work in molecular medicine has led to significant advancements in targeted therapeutic delivery. His contributions, particularly in the development of VNAR polypeptides and methods for crossing biological barriers, are