Company Filing History:
2 out of 2,168 
1 out of 16 Years Active: 1998-2012
Title: Innovator Myeong-Hee Yu: Pioneering Advances in Therapeutic Proteins
Introduction
Myeong-Hee Yu, an accomplished inventor based in Seoul, South Korea, has made significant contributions to the field of biochemistry through his innovative work on alpha-1-antitrypsin muteins. With a total of two patents to his name, his research focuses on enhancing the stability and efficacy of proteins used in therapeutic applications.
Latest Patents
One of Myeong-Hee Yu's most notable inventions is the "Thermostable alpha-1-antitrypsin mutein with a disulfide bond and the method for preparing it." This patent pertains to an alpha-1-antitrypsin mutein which demonstrates improved thermostability compared with conventional variants. By strategically substituting the 168th and 189th amino acids with cysteines, which are then linked by a disulfide bond, he successfully maintained the protein's functional activity. This developmental breakthrough offers great potential for therapeutic agents, ensuring stability within biological systems, and is applicable in the creation of diagnostic reagents as well as affinity columns.
Career Highlights
Throughout his career, Myeong-Hee Yu has been associated with reputable institutions, including the Korea Institute of Science and Technology and Korea Greencross Corporation. His work at these organizations has involved extensive research and development, focusing on protein engineering and its implications for medicine.
Collaborations
Myeong-Hee Yu has collaborated with distinguished coworkers such as Ki-Sun Kwon and Kee-Nyung Lee. These partnerships have fostered a collaborative environment for innovation and contributed to the advancement of protein-based therapeutics.
Conclusion
Myeong-Hee Yu's contributions to the field of biochemistry are underscored by his groundbreaking patents and collaborative efforts. His work on thermostable alpha-1-antitrypsin muteins not only enhances the stability of therapeutic proteins but also opens new avenues for their application in medicine. As an inventor, Yu's dedication to research continues to inspire advancements in therapeutic solutions for various medical challenges.