Location History:
- Helena, AL (US) (1999 - 2002)
- Birmingham, AL (US) (2003)
Company Filing History:
Years Active: 1999-2003
Title: Innovations by Inventor Murray A. Stackhouse
Introduction
Murray A. Stackhouse is a prominent inventor based in Birmingham, AL (US). He has made significant contributions to the field of cancer treatment through his innovative approaches. With a total of 5 patents, Stackhouse has focused on enhancing the effectiveness of cancer therapies.
Latest Patents
One of his latest patents is titled "Molecular chemotherapy enhancement of radiotherapy." This invention provides a new approach for cancer treatment by utilizing gene therapy combined with radiation therapy to enhance cytotoxicity in malignant cells. Specifically, it demonstrates that molecular chemotherapy with the cytosine deaminase gene and 5-fluorocytosine is an effective radiosensitizing strategy. This method may lead to substantial improvement in tumor control, with less normal tissue toxicity than conventional systemic administration of 5-fluorouracil, ultimately translating into improved cure rates and better survival. Additionally, the invention includes a noninvasive method for continuous in vivo monitoring of 5-fluorouracil production via magnetic resonance spectroscopy.
Another significant patent by Stackhouse is "Enhancement of tumor cell chemosensitivity and radiosensitivity using single chain secretory antibodies." This invention provides a method of enhancing the chemosensitivity and radiosensitivity of neoplastic cells expressing an oncoprotein that stimulates cell proliferation. The method involves introducing a nucleic acid molecule encoding an antibody homologue, which is expressed intracellularly and binds to the oncoprotein in the endoplasmic reticulum of the cell. This approach aims to enhance the inhibition of proliferation of neoplastic cells when combined with anti-neoplastic agents.
Career Highlights
Murray A. Stackhouse is associated with the UAB Research Foundation, where he continues to work on groundbreaking research in cancer therapies. His innovative work has garnered attention in the scientific community and has the potential to significantly impact cancer treatment protocols.
Collaborations
Throughout his career, Stackhouse has collaborated with notable colleagues, including Donald J. Buchsbaum and David T. Curiel. These collaborations have further enriched his research and contributed to the advancement of cancer treatment methodologies.
Conclusion
Murray A. Stackhouse is a distinguished inventor whose work in cancer treatment through innovative methodologies has the potential to change the landscape of oncology. His patents reflect a commitment to improving patient outcomes and advancing
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.