Company Filing History:
5 out of 1,153 
1 out of 10 Years Active: 1995-2000
Title: Murali K Tummuru: Innovator in Peptic Ulcer Research
Introduction
Murali K Tummuru is a notable inventor based in Nashville, TN (US). He has made significant contributions to the field of medical research, particularly in understanding peptic ulceration. With a total of 5 patents to his name, Tummuru's work has the potential to impact the diagnosis and treatment of gastric conditions.
Latest Patents
Tummuru's latest patents include groundbreaking inventions related to the TagA gene and methods for detecting predisposition to peptic ulceration. One of his notable inventions provides an isolated nucleic acid encoding an approximately 120-128 kilodalton antigen of Helicobacter pylori. This antigen is associated with peptic ulceration. The invention outlines methods for detecting the presence of a Helicobacter pylori strain that possesses this antigen in a subject. The detection process involves contacting an antibody-containing sample from the subject with a detectable amount of the TagA antigen and observing the binding of the antigen and the antibody. The presence of a strain expressing the TagA antigen indicates a predisposition to peptic ulceration and gastric carcinoma. Additionally, Tummuru's work includes a mutant H. pylori that does not express a functional TagA antigen.
Career Highlights
Throughout his career, Tummuru has worked with esteemed institutions such as Vanderbilt University and Oravax, Inc. His research has focused on the implications of Helicobacter pylori in gastrointestinal diseases, contributing to a deeper understanding of these conditions.
Collaborations
Tummuru has collaborated with prominent researchers in his field, including Martin J Blaser and Timothy L Cover. These collaborations have furthered the impact of his research and innovations.
Conclusion
Murali K Tummuru's contributions to the field of medical research, particularly in relation to peptic ulceration, highlight his role as an influential inventor. His patents and collaborations reflect a commitment to advancing healthcare through innovative solutions.