Conway, AR, United States of America

Mouad Abdulrahim

USPTO Granted Patents = 2 

 

Average Co-Inventor Count = 7.0

ph-index = 1

Forward Citations = 2(Granted Patents)


Company Filing History:


Years Active: 2022-2024

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2 patents (USPTO):Explore Patents

Title: Innovations by Mouad Abdulrahim: Advancements in Cancer Treatment

Introduction: Mouad Abdulrahim, an accomplished inventor based in Conway, Arkansas, has made significant contributions to the field of pharmacology. With two patents to his name, he has focused his research on developing methods and compositions for the inhibition of dihydroorotate dehydrogenase (DHODH). His innovative compounds are expected to play a crucial role in treating various disorders, particularly hematological cancers.

Latest Patents: Mouad Abdulrahim’s latest patents revolve around novel compounds known as 3,4,6,8-substituted-2-([1,1'-biphenyl]-4-yl)quinoline analogs. These compounds act as inhibitors of dihydroorotate dehydrogenase, showcasing improved pharmacokinetic properties. The applications of these compounds extend to the treatment of numerous diseases where DHODH inhibition could be clinically advantageous, including acute myeloid leukemia (AML), graft-versus-host diseases, autoimmune disorders, and conditions related to T-cell proliferation. Remarkably, these compounds can exhibit flip-flop kinetics, suggesting that their absorption may dominate their elimination when administered orally, thus presenting a sustained pharmacokinetic profile.

Career Highlights: Throughout his career, Mouad Abdulrahim has collaborated with key institutions such as the Ohio State Innovation Foundation and Hendrix College. His background in these esteemed organizations has allowed him to refine his research and innovate in the realm of drug development.

Collaborations: Mouad has had the opportunity to work alongside notable colleagues, including John C. Byrd and Thomas E. Goodwin. These partnerships have undoubtedly enriched his research and have contributed to the advancement of his groundbreaking inventions.

Conclusion: Mouad Abdulrahim's contributions to the field of pharmacology through his innovative patents demonstrate his commitment to improving medical treatments. With a focus on the inhibition of dihydroorotate dehydrogenase, his work holds promise for the future of cancer therapy and other significant health challenges, positioning him as a notable inventor in the domain of medical innovation.

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