Location History:
- Montréal, CA (2001)
- Cöte St-Luc, CA (2006)
- Cote St. Luc, CA (1996 - 2008)
Company Filing History:
5 out of 274 
4 out of 53 
3 out of 98 
Years Active: 1996-2008
Title: Moshe Szyf: Innovator in Cancer Research
Introduction
Moshe Szyf, located in Cote St. Luc, Canada, is a prominent inventor known for his significant contributions to cancer research. With a remarkable portfolio of 9 patents, his work primarily focuses on understanding and manipulating the mechanisms of DNA demethylation, which has profound implications in the field of oncology.
Latest Patents
Among his latest innovations are two groundbreaking patents:
1. **Oligonucleotide Inhibitors of MBD2/DNA Demethylase and Uses Thereof** - This patent presents oligonucleotide inhibitors capable of inhibiting the expression of a mammalian MBD2/DNA demethylase (MBD2/dMTase). These inhibitors are designed to restrict the growth or proliferation of tumor cells, both in vitro and in vivo. This invention not only opens new avenues for cancer treatment but also provides methodologies for identifying potential target genes that may be significant in cancer therapy or diagnosis.
2. **DNA Demethylase, Therapeutic and Diagnostic Uses Thereof** - This patent pertains to a DNA demethylase enzyme with a molecular weight of approximately 40 KDa, which is notably overexpressed in cancer cells compared to normal cells. The therapeutic and diagnostic applications of this enzyme are pivotal for advancing cancer treatment strategies.
Career Highlights
Moshe Szyf has had an impressive career, serving in pivotal roles at reputable institutions such as McGill University and Methylgene, Inc. His research has profoundly influenced the understanding of cancer biology and the development of novel therapeutic approaches.
Collaborations
Throughout his career, Szyf has collaborated with accomplished professionals in his field, including Pascal Bigey and Shyam Ramchandani. These collaborations have enriched his research and contributed to the advancement of therapeutic strategies against cancer.
Conclusion
In conclusion, Moshe Szyf is a noteworthy inventor whose innovative patents are making significant strides in cancer research. His work in the realm of DNA demethylation holds potential for new therapeutic and diagnostic modalities, reflecting his commitment to improving cancer treatment and patient outcomes.