Location History:
- Schodack, NY (US) (1981 - 1982)
- Greenbush, NY (US) (1982)
- East Greenbush, NY (US) (1982 - 1983)
Company Filing History:
Years Active: 1981-1983
Title: Monte D Gruett: Innovator in Cardiotonic Compounds
Introduction
Monte D Gruett is a notable inventor based in Schodack, NY (US), recognized for his contributions to the field of cardiotonics. He holds a total of 8 patents, showcasing his innovative approach to enhancing cardiac function through chemical compounds.
Latest Patents
Among his latest patents are the development of 5-(Pyridinyl)-1H-pyrazolo[3,4-b] pyridines and their cardiotonic use. These compounds are prepared by reacting a .alpha.-PY-.beta.dimethylamino-acrolein with 5-amino-1-R-3-R'-1H-pyrazole, where R represents lower-alkyl or lower-hydroxyalkyl, and R' is either hydrogen or lower-alkyl. Additionally, he has developed 5-(Pyridinyl)-1H-pyrazolo[3,4-b]pyridin-3-amines, which are also useful as cardiotonics. These compounds are synthesized through various chemical reactions involving lower-alkanoic acids and reducing agents, demonstrating his expertise in medicinal chemistry.
Career Highlights
Monte D Gruett has had a significant career, contributing to the pharmaceutical industry through his innovative research and development. He has worked with Sterling Drug Inc., where he applied his knowledge to create impactful cardiotonic compositions.
Collaborations
Throughout his career, Gruett has collaborated with notable individuals such as George Y Lesher and Donald F Page, further enhancing his contributions to the field.
Conclusion
Monte D Gruett's work in developing cardiotonic compounds has made a significant impact in the medical field. His innovative patents and collaborations highlight his dedication to improving cardiac health through scientific advancements.