Monica Chadha

Title: Monica Chadha: Innovator in Genetic Analysis

Introduction

Monica Chadha is a prominent inventor based in Fremont, CA (US). She has made significant contributions to the field of genetic analysis, holding 2 patents that focus on innovative methods for analyzing mixed nucleic acid populations. Her work has implications for prenatal testing and cancer diagnostics, showcasing her commitment to advancing medical technology.

Latest Patents

Monica's latest patents include "Array-based methods for analysing mixed samples using differently labelled allele-specific probes." This disclosure provides methods and systems useful in array-based analysis of mixed nucleic acid populations. It includes multiplex genotyping of a mixed nucleic acid sample and detecting differences in copy number of a target polynucleotide and/or a target chromosome, such as microdeletions, duplications, and aneuploidies. The methods are designed for the diagnosis of genetic abnormalities in non-invasive samples taken from organisms, such as blood, plasma, serum, urine, stool, or saliva. The disclosed methods find applications in prenatal testing and cancer diagnostics, utilizing the hybridization of amplified fragments from the sample and molecular inversion probes (MIP) to an oligonucleotide array.

Career Highlights

Throughout her career, Monica has worked with notable companies, including Affymetrix, Inc. Her experience in these organizations has allowed her to develop and refine her innovative techniques in genetic analysis.

Collaborations

Monica has collaborated with esteemed colleagues, including Ronald J Sapolsky and Michael H Shapero. These partnerships have contributed to her success and the advancement of her research.

Conclusion

Monica Chadha's contributions to genetic analysis through her innovative patents and collaborations highlight her role as a leading inventor in the field. Her work continues to impact prenatal testing and cancer diagnostics, making significant strides in medical technology.