Company Filing History:
Years Active: 2022-2024
Title: Innovations by Mohammed Ghonime in Genetic Engineering
Introduction
Mohammed Ghonime is a prominent inventor based in Cambridge, MA (US), known for his significant contributions to the field of genetic engineering. He holds a total of four patents that focus on enhancing the functionality and persistence of genetically engineered T cells. His work has the potential to revolutionize cancer treatment and immunotherapy.
Latest Patents
Ghonime's latest patents involve genetically engineered T cells that feature disruptions in the Regnase-1 and/or TGFBRII genes. These innovations lead to improved cell growth activity, enhanced persistence, and reduced T cell exhaustion. Additionally, the engineered T cells exhibit enhanced cytotoxicity activity and resistance to inhibitory effects induced by TGF-b and fibroblasts. Such advancements mark a significant step forward in the development of more effective immunotherapies.
Career Highlights
Ghonime is currently associated with Crispr Therapeutics AG, a company at the forefront of gene editing technology. His work there focuses on applying CRISPR technology to develop innovative therapies that can address various medical challenges. His contributions have been instrumental in advancing the understanding and application of genetic modifications in T cells.
Collaborations
Ghonime collaborates with notable colleagues, including Mary-Lee Dequeant and Demetrios Kalaitzidis. Their combined expertise fosters a collaborative environment that enhances the research and development of groundbreaking therapies.
Conclusion
Mohammed Ghonime's innovative work in genetic engineering, particularly in the realm of T cell modifications, showcases his commitment to advancing medical science. His patents and collaborations reflect a dedication to improving therapeutic outcomes for patients.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.