Location History:
- Saint Louis, MO (US) (2019)
- St. Louis, MO (US) (2020)
Company Filing History:
Years Active: 2019-2020
Title: Innovations by Mohammad Wadud Bhuiya: Pioneering Enzyme Technologies in St. Louis
Introduction
Mohammad Wadud Bhuiya is an accomplished inventor based in St. Louis, MO, renowned for his significant contributions to biochemistry and enzymatic processes. With a total of two patents to his name, Bhuiya's innovative work focuses on biosynthesis and the development of sustainable methods for producing valuable chemical compounds.
Latest Patents
One of Bhuiya's latest patents involves enzymes and methods for styrene synthesis. This technology relates to the biosynthesis of styrene, recognizing the conversion of phenylalanine into styrene through a two-step pathway involving deamination and decarboxylation. The process utilizes trans-cinnamic acid as an intermediate, and two types of enzymes play critical roles: phenylalanine ammonia lyase (PAL) converts phenylalanine to trans-cinnamic acid, while cinnamic acid decarboxylase transforms trans-cinnamic acid into styrene. By cultivating host cells expressing these enzymes in a bioreactor, styrene can be produced from renewable substrates like glucose.
Another notable patent by Bhuiya details methods for the biosynthetic production of pterostilbene. This method includes expressing a 4-coumarate- coenzyme A ligase (4CL) and stilbene synthase (STS), as well as a resveratrol O-methyltransferase (ROMT) within a cellular system. The process involves feeding p-coumaric acid into the system, growing the cells in an appropriate medium, and ultimately producing pterostilbene, a compound known for its health benefits.
Career Highlights
Throughout his career, Bhuiya has worked with leading companies in the biotechnology sector, including Phytogene, Inc. and Conagen Inc. His expertise and innovative approaches have positioned him as a valuable contributor to developing sustainable bioprocesses and innovative enzyme applications.
Collaborations
Bhuiya has collaborated with distinguished colleagues, including Xiaodan Yu and Hui Chen, contributing to a dynamic research environment that fosters creativity and innovation in biochemistry.
Conclusion
In summary, Mohammad Wadud Bhuiya's pioneering work in enzyme technologies and biosynthetic processes holds great promise for sustainable chemical production. His patents not only showcase his inventive spirit but also play a crucial role in advancing the field of biotechnology towards environmentally friendly solutions.