Mohammad Shahrokh Esfahani

Title: Mohammad Shahrokh Esfahani: Innovator in Cancer Detection Technologies

Introduction

Mohammad Shahrokh Esfahani is an accomplished inventor based in Mountain View, CA (US). He is affiliated with Leland Stanford Junior University, where he contributes to advancements in cancer detection technologies. Despite having no granted patents, his work is significant in the field of analyzing cell-free nucleic acids.

Latest Patent Applications

Esfahani's latest patent applications include innovative methods for analyzing cell-free nucleic acids and their applications. One application describes processes and materials to detect neoplasms from a biopsy. It outlines methods to build a sequencing library and perform targeted sequencing. Additionally, it addresses processes to mitigate confounding sources, allowing for the sequencing of cell-free nucleic acids to detect sequences derived from neoplasms. Another application, titled "System and Method for Gene Expression and Tissue of Origin Inference from Cell-Free DNA," provides methods for non-invasively determining the expression of genes of interest. This method aids in cancer classification and treatment stratification. It utilizes an integrated analytic approach, deriving a single biomarker from promoter fragment entropy and analyzing nucleosome-depleted regions. The methods are designed to use non-invasive blood draws, robustly identifying patients who will benefit from immune checkpoint inhibition and determining cancer subtype classification and tumor burden.

Conclusion

Mohammad Shahrokh Esfahani is a notable figure in the realm of cancer detection technologies, with a focus on innovative methods for analyzing cell-free nucleic acids. His contributions have the potential to significantly impact cancer diagnosis and treatment strategies.