Company Filing History:
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1 out of 833,002 Years Active: 2017-2024
Title: Mohammad Shahidul Islam: Innovator in Cancer Treatment
Introduction
Mohammad Shahidul Islam is a prominent inventor based in Riyadh, Saudi Arabia. He has made significant contributions to the field of cancer treatment through his innovative research and development. With a total of 3 patents, his work focuses on advanced formulations that target cancer cells effectively.
Latest Patents
One of his latest patents is titled "Nanoformulation of spirooxindole and methods for treating hepatocellular carcinoma." This innovative spirooxindole nanoformulation includes a proniosome loaded with a spirooxindole derivative. The spirooxindole derivative comprises a compound known as Compound 4d, which features substituted spirooxindoles that act as MDM2-p53 inhibitors. These inhibitors bear a benzylidine (styryl) arm and possess a complex fused ring system that is ideally suited for binding to the MDM2 protein. This binding interrupts the protein-protein interaction (PPI), which is crucial in cancer progression. Sixteen compounds, designated 4a-4p, were synthesized using a simple smooth method that employs an asymmetric 1,3-dipolar reaction as the key step. Testing has shown that these compounds exhibit anti-cancer activity against various forms of cancer cells affecting humans.
Career Highlights
Throughout his career, Mohammad Shahidul Islam has worked with notable institutions, including King Saud University. His research has been pivotal in advancing the understanding and treatment of cancer, particularly hepatocellular carcinoma.
Collaborations
He has collaborated with esteemed colleagues such as Assem Barakat and Abdullah Mohammed Al Majid, contributing to a rich exchange of ideas and expertise in the field of cancer research.
Conclusion
Mohammad Shahidul Islam's innovative work in cancer treatment through his patented formulations highlights his commitment to advancing medical science. His contributions are paving the way for more effective therapies in the fight against cancer.