Miyabishara Yokoyama

Title: Miyabishara Yokoyama: Innovator in APP Cleavage Activity Control

Introduction

Miyabishara Yokoyama is a notable inventor based in Tokyo, Japan. He has made significant contributions to the field of biochemistry, particularly in the area of Alzheimer's disease research. His innovative work focuses on methods for screening substances that control APP cleavage activity.

Latest Patents

Yokoyama holds a patent for a "Screening method for APP cleavage activity-controlling substances of ADAMTS4." This invention provides a method for screening a substance that controls APP669 N-terminal cleavage activity. The method involves causing a candidate substance to act on a cultured cell, measuring an Aβ-related peptide produced from the cultured cell, and evaluating APP669 N-terminal cleavage activity. The candidate substances can include low molecular weight compounds, peptides, proteins, and nucleic acids. Additionally, the invention provides an APP669 N-terminal cleavage enzyme containing ADAMTS4.

Career Highlights

Throughout his career, Miyabishara Yokoyama has worked with prominent organizations, including Shimadzu Corporation and The University of Tokyo. His experience in these institutions has allowed him to develop and refine his innovative ideas in the field of biochemistry.

Collaborations

Yokoyama has collaborated with various professionals in his field, including his coworker Naoki Kaneko. These collaborations have contributed to the advancement of his research and the successful development of his patented methods.

Conclusion

Miyabishara Yokoyama is a distinguished inventor whose work in screening methods for APP cleavage activity has the potential to impact Alzheimer's disease research significantly. His contributions to the field highlight the importance of innovation in addressing complex health challenges.