IDiyas

For the Inventor, By the Inventor

Ibaraki, Japan

Mitsuhiro Wakimasu

USPTO Granted Patents = 25

Average Co-Inventor Count = 3.3

ph-index = 6

Forward Citations = 93(Granted Patents)


Location History:

  • Osaka, JA (1977)
  • Suita, JA (1976 - 1978)
  • Takarazuka, JP (1980 - 1982)
  • Suita, JP (1982 - 1988)
  • Osaka, JP (1983 - 2000)
  • Tsukuba, JP (1994 - 2002)
  • Ibaraki, JP (1994 - 2003)

Company Filing History:

goldMedal25 out of 1,858 
 
Takeda Chemical Industries, Inc.
 patents

Years Active: 1976-2003

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25 patents (USPTO):Explore Patents
1. 6610655 - Pentapeptide with specific conformation, its production and use (2003-08-26),
2. 6346604 - Method for controlling conformation of cyclopentapeptide (2002-02-12),
3. 6147051 - Methods and compositions for the prophylactic and/or therapeutic (2000-11-14),
4. 5965526 - Pentapeptide with specific conformation, its production and use (1999-10-12),
5. 5948754 - Cyclic hexapeptides, their production and use (1999-09-07),
6. 5883075 - Cyclic endothelin antagonists (1999-03-16),
7. 5753619 - Composition for prophylaxis or treatment of pulmonary circulatory (1998-05-19),
8. 5616684 - Cyclic peptides and use thereof (1997-04-01),
9. 5478809 - TAN-1511, its derivatives, production and use thereof (1995-12-26),
10. 5478808 - 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and (1995-12-26),
11. 5352659 - Endothelin analogs and uses thereof (1994-10-04),
12. 5330978 - Phosphonic acid derivatives and use thereof (1994-07-19),
13. 5306808 - Peptide derivatives having vasodilating activity (1994-04-26),
14. 5159061 - Atrial natriuretic peptide derivative (1992-10-27),
15. 4748154 - Peptide derivatives, their production and use (1988-05-31),

**Title: Mitsuhiro Wakimasu - A Pioneer in Cyclic Pentapeptide Innovations**

Introduction

Mitsuhiro Wakimasu, based in Ibaraki, Japan, is a distinguished inventor known for his significant contributions to the field of cyclic pentapeptides. With a remarkable portfolio of 25 patents, his work has the potential to influence various biological applications and pharmaceutical developments.

Latest Patents

Wakimasu's latest patents include a groundbreaking invention titled "Pentapeptide with specific conformation, its production and use". This patent discloses cyclic pentapeptides featuring the formula (I)-Cyclo(-A -A -A -A -A -), where A positions are designated for specific amino acid residues. This innovative design allows the pentapeptide to form both gamma (γ) and beta (β) turns, which are crucial for its biological activity. By utilizing D-α-amino acid residues for certain positions and L-α-amino acid residues for others, Wakimasu has enabled the synthesis of compounds tailored for enhanced biological efficacy. This invention paves the way for designing biologically active compounds critical for various therapeutic applications.

Career Highlights

Throughout his career, Mitsuhiro Wakimasu has been associated with Takeda Chemical Industries, Inc., one of the leading pharmaceutical firms. His extensive research and dedication have led to numerous innovations, particularly in peptide design, which are essential for drug development.

Collaborations

Wakimasu has worked alongside notable colleagues such as Masahiko Fujino and Takashi Kikuchi, sharing insights and expertise in their mutual pursuit of advancing peptide technology and its applications in medicine.

Conclusion

Mitsuhiro Wakimasu's work in cyclic pentapeptides exemplifies the intersection of innovation and scientific research. His contributions not only enrich the field of biochemistry but also hold promise for advancements in the biopharmaceutical industry. As he continues to develop innovative solutions, the impact of his inventions is expected to resonate across various sectors of healthcare and drug discovery.

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