Mistuni Ghosh

Title: The Innovations of Mistuni Ghosh

Introduction

Mistuni Ghosh is an accomplished inventor based in Santa Clara, CA. He has made significant contributions to the field of molecular biology, particularly in the area of fluorescence in situ hybridization. His innovative work has led to the development of a patented method that enhances the detection of target nucleic acids.

Latest Patents

Mistuni Ghosh holds a patent for "Signal amplification of fluorescence in situ hybridization." This patent outlines a method that includes several key steps: obtaining a labeled nucleic acid probe complementary to a target nucleic acid, hybridizing the probe with the target nucleic acid in a fixed cell to produce a duplex, linking the probe in the duplex to a peroxidase conjugate via a capture tag, and incubating the peroxidase-labeled duplex with a peroxidase substrate. The peroxidase activity catalyzes the deposition of the substrate near the duplex, resulting in a detectable signal. This innovative approach significantly improves the sensitivity of nucleic acid detection.

Career Highlights

Mistuni Ghosh is currently employed at Agilent Technologies, Inc., where he continues to advance his research and development efforts. His work at Agilent has allowed him to collaborate with other talented professionals in the field, further enhancing the impact of his inventions.

Collaborations

Some of his notable coworkers include Kristin Briana Bernick and Robert A Ach. Their collaborative efforts contribute to the innovative environment at Agilent Technologies, fostering advancements in technology and research.

Conclusion

Mistuni Ghosh's contributions to the field of molecular biology through his patented methods demonstrate his commitment to innovation and excellence. His work not only enhances scientific understanding but also paves the way for future advancements in nucleic acid detection.