This inventor holds 4 USPTO granted patents. Top assignees: Spofa, Spojene Podniky Pro Zdravotnickou Vyrobu, Spofa United Pharmaceutical Works. Active years: 1980-1987.
Company Filing History:
3 out of 16 
1 out of 8 Years Active: 1980-1987
Title: Miroslav Protiva: Innovator in Neuroleptic Compounds
Introduction
Miroslav Protiva is a notable inventor based in Prague, Czech Republic. He has made significant contributions to the field of pharmacology, particularly in the development of neuroleptic compounds. With a total of 4 patents, his work has garnered attention for its potential therapeutic applications.
Latest Patents
Protiva's latest patents include innovative compounds such as N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo (B,F) and N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo(b,f)thiepins. These compounds are characterized by their general formula, where R represents various functional groups, including aminocarbonyl and amino-oximinomethyl. They are recognized for their high potency as antidopaminergic, non-cataleptic neuroleptics, which are particularly useful in treating schizophrenia. Recent pharmacological assays suggest that these compounds may be free from the common extrapyramidal side effects associated with traditional neuroleptics. The compounds can be synthesized using standard preparative methods and can be neutralized with suitable acids to create addition salts for therapeutic use.
Career Highlights
Throughout his career, Protiva has worked with several prominent companies in the pharmaceutical industry. Notable among these are Spofa, Spojene Podniky Pro Zdravotnickou Vyrobu, and Spofa United Pharmaceutical Works. His experience in these organizations has contributed to his expertise in drug development and innovation.
Collaborations
Protiva has collaborated with esteemed colleagues such as Karel Sindelar and Antonin Dlabac. These partnerships have likely enhanced his research and development efforts, leading to significant advancements in his field.
Conclusion
Miroslav Protiva's contributions to the field of neuroleptics demonstrate his innovative spirit and commitment to improving therapeutic options for patients. His patents reflect a deep understanding of pharmacology and a dedication to advancing medical science.