Miri Cohen-Zinder

Title: Miri Cohen-Zinder: Innovator in Agricultural Research

Introduction

Miri Cohen-Zinder is a notable inventor and researcher based in Israel. She has made significant contributions to the field of agricultural research, particularly in the study of bovine genetics. Although she currently holds no granted patents, her work has the potential to impact the dairy industry significantly.

Latest Patent Applications

Miri Cohen-Zinder's latest patent application is titled "Bovine Abcg2 Gene Missense Mutations And Uses Thereof." This application focuses on a quantitative trait locus (QTL) affecting milk fat and protein concentration, localized to a 4cM confidence interval on chromosome 6 centered on the microsatellite BM143. The research characterizes genes and sequence variation in this region, identifying common haplotypes spanning five polymorphic sites in the genes IBSP, SPP1, PKD2, and ABCG2 for two sires heterozygous for this QTL. The expression of SPP1 and ABCG2 in the bovine mammary gland increases from parturition through lactation. The study sequenced SPP1 and all coding exons of ABCG2 and PKD2 for these two sires. Notably, a single nucleotide change capable of encoding a substitution of tyrosine-581 to serine (Y581S) in the ABCG2 transporter was identified as the only polymorphism corresponding to the segregation status of all three heterozygous and 15 homozygous sires for the QTL in the Israeli and US Holstein populations.

Conclusion

Miri Cohen-Zinder's research exemplifies the intersection of genetics and agriculture, showcasing her commitment to advancing the dairy industry through innovative scientific inquiry. Her contributions, although not yet reflected in granted patents, hold promise for future developments in bovine genetics.