Mirdza E Neiders

Title: Mirdza E Neiders: Innovator in Monoclonal Antibodies

Introduction

Mirdza E Neiders is a prominent inventor based in Amherst, NY (US). She has made significant contributions to the field of microbiology through her innovative work on monoclonal antibodies. Her research focuses on the identification of microorganisms, particularly those implicated in dental diseases.

Latest Patents

Mirdza E Neiders holds a patent for "Monoclonal antibodies useful in the identification of microorganisms - Actinobacillus actinomycetemcomitans." This invention is crucial as Actinobacillus actinomycetemcomitans has frequently been implicated in juvenile periodontitis. The monoclonal antibodies developed by Neiders are specific to this bacterium and are typically employed as reagents that include an inert carrier, preferably a liquid such as buffered saline solution and a preservative. The carrier compositions are carefully selected to ensure proper dispersal of bacteria and to preserve the integrity of antigens and supplemental structures. This selection is especially important in detecting mixtures that include bacteria producing large amounts of autolytic enzymes, such as B. gingivalis. The monoclonal antibodies are useful in clinical testing and differentiating antigens in gingival or subgingival sera. The method involves contacting a sample of bacterial flora from a lesion with a measured amount of monoclonal antibody specific to a single antigen site on Actinobacillus actinomycetemcomitans and subsequently measuring the number of antibody-antigen complexes formed.

Career Highlights

Mirdza E Neiders is affiliated with the State University of New York, where she continues her research and development in the field of microbiology. Her work has garnered attention for its potential applications in clinical diagnostics and treatment.

Collaborations

Throughout her career, Mirdza has collaborated with notable colleagues, including Robert J Genco and Joseph J Zambon. These collaborations have furthered her research and contributed to advancements in the understanding of microbial identification.

Conclusion

Mirdza E Neiders is a trailblazer in the field of monoclonal antibodies, with her innovative patent playing a vital role in the identification of microorganisms related to dental health. Her contributions continue to impact clinical practices and enhance our understanding of microbial interactions.