Company Filing History:
Years Active: 2014-2015
Title: Minyong Li: Innovator in Glycosylation and Quorum Sensing
Introduction
Minyong Li is a prominent inventor based in Shandong, China. He has made significant contributions to the fields of biochemistry and molecular biology, particularly in the development of innovative methods for targeting glycosylated proteins and regulating bacterial quorum sensing.
Latest Patents
Minyong Li holds two notable patents. The first patent focuses on nucleotides and aptamers containing boronic acid groups that exhibit biased binding to glycosylated proteins. This invention encompasses oligonucleotide aptamers that selectively bind to target glycosylated polypeptides or proteins, utilizing a boronic acid linked to a nucleosidic base of nucleotides. The methods described in this patent allow for the isolation and amplification of aptamers that can selectively bind to glycosylation sites, providing valuable tools for detecting glycosylated species.
The second patent involves compounds and compositions that serve as specific AI-2 antagonists for controlling bacterial quorum sensing. Although these antagonists do not have a bactericidal effect, they can attenuate virulence, drug resistance, and biofilm formation, offering therapeutic benefits. The methods outlined in this patent are designed to inhibit microbial virulence and prevent the formation of extensive biofilms, which can pose health risks and physical issues.
Career Highlights
Minyong Li is affiliated with the Georgia State University Research Foundation, Inc., where he continues to advance his research and innovations. His work has garnered attention for its potential applications in medical and environmental fields.
Collaborations
He has collaborated with notable colleagues, including Binghe Wang and Zhen Qiu Huang, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Minyong Li's contributions to the fields of glycosylation and quorum sensing highlight his role as an influential inventor. His patents reflect a commitment to advancing scientific knowledge and developing practical solutions to complex biological challenges.