Minna Nyström

Title: Minna Nyström - Innovator in DNA Mismatch Repair Function

Introduction

Minna Nyström is a notable inventor based at Helsingin Yliopisto in Finland. She has made significant contributions to the field of genetics, particularly in the area of DNA mismatch repair. Her innovative work has the potential to enhance diagnostic methods for various genetic disorders.

Latest Patents

Minna Nyström holds a patent for a method to determine DNA mismatch repair function. This invention relates to a quantitative method for assessing whether a human subject has an impaired DNA mismatch repair function. The process involves providing a diagnostic sample from the human subject and producing a nuclear extract from that sample. It includes the use of MMR proficient and MMR deficient nuclear extracts as positive and negative controls, respectively. The method combines each nuclear extract with at least one mismatch bearing substrate DNA molecule, performs a mismatch repair assay, and determines the capability of the sample nuclear extract to repair the substrate DNA molecule. The invention also includes a kit that provides the necessary reagents for use in this method.

Career Highlights

Minna Nyström's career at Helsingin Yliopisto has been marked by her dedication to advancing genetic research. Her work has not only contributed to scientific knowledge but also has practical applications in diagnostics. She has been recognized for her innovative approach to complex genetic issues.

Collaborations

Minna collaborates with esteemed colleagues such as Minttu Kansikas and Päivi Peltomäki. These collaborations enhance the research environment and foster innovation in their shared field of study.

Conclusion

Minna Nyström's contributions to the field of DNA mismatch repair function exemplify the impact of innovative research in genetics. Her patent and collaborative efforts continue to pave the way for advancements in diagnostic methods.