Location History:
- Baltimore, MD (US) (2008 - 2011)
- Clarksville, MD (US) (2015)
Company Filing History:
Years Active: 2008-2015
Title: Innovations in Cancer Research by Mingzhao Michael Xing
Introduction
Mingzhao Michael Xing is a prominent inventor based in Clarksville, MD (US), known for his significant contributions to cancer research. He holds three patents that focus on the genetic mechanisms underlying various cancers, particularly thyroid cancer. His work has implications for both prognosis and therapeutic strategies in oncology.
Latest Patents
One of his latest patents involves the genetic amplification of IQGAP1 in cancer. This research examined the relationship between IQGAP1 copy gain and clinicopathologic outcomes of thyroid cancer. The study found that IQGAP1 copy number gain was present in a range of thyroid tumors, with a notable correlation to tumor invasiveness. The findings suggest that IQGAP1 plays a crucial role in the invasiveness of thyroid cancer and could serve as a valuable prognostic marker and therapeutic target.
Another significant patent focuses on the BRAF gene, which is frequently mutated in human cancers, especially malignant melanoma. In this study, 476 primary tumors were tested for the BRAF T1796A mutation. The results indicated that this mutation is prevalent in papillary thyroid carcinomas and may predict poor prognosis for patients. This research underscores the importance of BRAF mutations in the development of thyroid cancer.
Career Highlights
Mingzhao Michael Xing is affiliated with The Johns Hopkins University, where he conducts groundbreaking research in cancer genetics. His work has not only advanced the understanding of thyroid cancer but has also contributed to the broader field of oncology. His innovative approaches have garnered attention and respect within the scientific community.
Collaborations
Throughout his career, Mingzhao has collaborated with notable researchers, including David Sidransky and Yoram Cohen. These collaborations have enriched his research and expanded the impact of his findings in cancer biology.
Conclusion
Mingzhao Michael Xing's contributions to cancer research through his patents and collaborations highlight the importance of genetic factors in cancer progression. His work continues to pave the way for new diagnostic and therapeutic strategies in oncology.