Min Li

Title: Innovations of Min Li: Solid Phase Synthesis of 1-Aminohydantoins

Introduction

Min Li, an accomplished inventor residing in West Chester, OH, has made significant contributions to the field of chemistry through his innovative patent related to the synthesis of 1-aminohydantoin compounds. With a focus on improving synthetic methodologies, his work demonstrates a keen understanding of chemical processes that could have important implications in various applications.

Latest Patents

Min Li holds one patent titled "Solid Phase Synthesis of 1-Aminohydantoins." The patent outlines a detailed process that involves using solid support resin to synthesize 1-aminohydantoin compounds. The method consists of several critical steps: First, a resin-bound protected α-hydrazinyl ester is prepared by reacting the resin with an α-bromo carboxylic acid and then with a protected hydrazine. Alternatively, it can involve reacting the resin directly with a protected α-hydrazinyl carboxylic acid. Following this, a resin-bound imine is formed through deprotection of the hydrazinyl moiety and subsequent reaction with an aldehyde or ketone. The process continues with preparing a resin-bound secondary urea and ultimately yielding the 1-aminohydantoin compound after removing the secondary urea from the resin and introducing cyclization.

Career Highlights

Min Li is affiliated with The Procter & Gamble Company, where he applies his expertise in chemical synthesis to contribute to the advancement of innovative products. His career has been marked by a commitment to research and development, which has yielded significant breakthroughs in synthetic chemistry.

Collaborations

While at The Procter & Gamble Company, Min Li has collaborated with esteemed coworkers, including Lawrence Joseph Wilson and David Edward Portlock. Their combined efforts illustrate the importance of teamwork in driving innovation and achieving successful outcomes in their research projects.

Conclusion

Min Li's work in the solid phase synthesis of 1-aminohydantoins represents a noteworthy advancement in the field of chemistry. His innovative approach and dedication to his craft not only reflect his individual talent but also the collective spirit of collaboration within The Procter & Gamble Company. As science continues to evolve, inventors like Min Li play a crucial role in shaping the future of chemical advancements.