Company Filing History:
Years Active: 2014-2016
Title: Miles Miller: Innovator in Cellular Engineering
Introduction
Miles Miller is a prominent inventor based in Indianapolis, IN (US). He has made significant contributions to the field of cellular engineering, particularly in programming mammalian cells for desired functions. With a total of 2 patents, his work is paving the way for advancements in stem cell research and applications.
Latest Patents
Miller's latest patents focus on engineered cellular pathways for programmed autoregulation of differentiation. The inventions provide compositions and methods for programming mammalian cells, specifically stem cells, to differentiate into desired cell types. A quorum sensing system is introduced into mammalian host cells, which regulates the expression of cell fate regulators. This system comprises vectors that express components of a bacterial quorum sensing pathway, including proteins that catalyze the synthesis of an autoinducer and a gene encoding a regulatory partner of the autoinducer. Additionally, the vectors link genes encoding cell fate regulators to a promoter induced by the autoinducer/regulatory partner complex. The system can also include vectors with genes linked to a promoter induced by a factor synthesized in response to a first stage of differentiation, triggering a second stage of differentiation.
Career Highlights
Miles Miller is affiliated with Princeton University, where he continues to innovate and contribute to the scientific community. His work has garnered attention for its potential applications in regenerative medicine and biotechnology.
Collaborations
Miller has collaborated with notable colleagues, including Ron Weiss and Ihor R Lemischka, who share his passion for advancing cellular engineering and stem cell research.
Conclusion
Miles Miller's contributions to the field of cellular engineering are noteworthy, and his innovative patents reflect his commitment to advancing scientific knowledge. His work continues to inspire future research and applications in the realm of stem cell technology.