Miguel A Alonso

Title: The Innovations of Miguel A. Alonso

Introduction

Miguel A. Alonso is a notable inventor based in Madrid, Spain. He has made significant contributions to the field of biochemistry, particularly in the development of antitumoral compounds. With a total of 2 patents, his work has garnered attention in both academic and medical circles.

Latest Patents

Alonso's latest patents include innovative antitumoral compounds, specifically Azaanthracene-triones. These compounds are characterized by a specific formula where R.sup.1, R.sup.2, R.sup.4, and R.sup.5 can be hydrogen atoms or lower alkyl groups. Additionally, he has discovered a T-cell membrane protein weighing 16.7 kilodaltons, which is produced in mature T cells but not in early-stage T cells. This protein features four distinct amphipathic domains, each with an amino acid composition that suggests a stable alpha helical structure in a lipid bilayer. The regions are flanked by polar domains, and an antibody specific to one of these polar domains can effectively discriminate mature T-cells in mixed-cell samples.

Career Highlights

Throughout his career, Miguel A. Alonso has worked with prestigious institutions such as Yale University and Universidad Complutense De Madrid. His research has significantly advanced the understanding of T-cell biology and potential cancer therapies.

Collaborations

Alonso has collaborated with esteemed colleagues, including Sherman M. Weissman and Carmen Avendano. Their joint efforts have contributed to the advancement of knowledge in their respective fields.

Conclusion

Miguel A. Alonso's innovative work in the field of biochemistry, particularly in antitumoral compounds and T-cell biology, highlights his importance as an inventor. His contributions continue to influence research and development in cancer therapies.