Company Filing History:
Years Active: 2007
Title: Mieczyslaw Marcinkiewicz: Innovator in Proteinase Research
Introduction
Mieczyslaw Marcinkiewicz is a notable inventor based in Outremont, Canada. He has made significant contributions to the field of proteinase research, particularly through his innovative patent related to subtilisin/kexin isozyme SKI-1. His work has implications for therapeutic applications, showcasing the importance of his research in the scientific community.
Latest Patents
Marcinkiewicz holds a patent titled "Mammalian Subtilisin/kexin isozyme SKI-1: a proprotein convertase with a unique cleavage specificity." This patent describes the identification of a highly conserved type-I membrane-bound proteinase called SKI-1, which exhibits unique cleavage specificity. The research highlights the proteinase's role in processing proBDNF and its potential therapeutic applications through the development of SKI-1 inhibitors.
Career Highlights
Mieczyslaw Marcinkiewicz is affiliated with the Institut De Recherches Cliniques De Montreal, where he has conducted extensive research on serine proteinases. His work has led to the discovery of the SKI-1 proteinase, which has been shown to have a wide pH optimum for cleavage and is dependent on calcium. His findings have opened new avenues for understanding proteinase functions and their applications in medicine.
Collaborations
Marcinkiewicz has collaborated with esteemed colleagues such as Nabil G Seidah and Michel Chretien. These collaborations have enriched his research and contributed to the advancement of knowledge in the field of proteinases.
Conclusion
Mieczyslaw Marcinkiewicz's innovative work in proteinase research, particularly with SKI-1, underscores his importance as an inventor in the scientific community. His contributions have the potential to lead to significant therapeutic advancements.