Company Filing History:
Years Active: 2010-2021
Title: **Michelle Winn: Innovator in Kidney Disorders**
Introduction
Michelle Winn, an accomplished inventor based in Durham, North Carolina, has made significant contributions to the field of medical research, specifically in understanding kidney disorders. With a remarkable portfolio of five patents, her work emphasizes the importance of genetic factors in kidney disease pathogenesis.
Latest Patents
Among her latest inventions is a patent concerning the role of TRPC6 in glomerulonephritis, particularly in Focal and Segmental Glomerulosclerosis (FSGS). This disorder is characterized by damage to specific parts of the kidney, leading to serious health implications. The patent highlights a missense mutation in the TRPC6 gene located on chromosome 11q, which encodes the ion channel protein Transient Receptor Potential Cation Channel 6. This mutation, specifically a P112Q substitution, has been shown to enhance TRPC6-mediated calcium signals, particularly in response to agonists such as angiotensin II, while also altering the protein's intracellular distribution. Her findings provide novel insights into the mechanisms underlying glomerular disease pathogenesis.
Career Highlights
Michelle Winn has spent her career at Duke University, where she has engaged in pioneering research on hereditary kidney diseases. Her experience and expertise in the field of nephrology have positioned her as a key contributor to the understanding of glomerular dysfunctions.
Collaborations
Throughout her career, Michelle has collaborated with fellow researchers such as Margaret A Pericak-Vance and Jeffery M Vance. These partnerships have furthered her research initiatives and enhanced the impact of her discoveries on kidney disease.
Conclusion
Michelle Winn's innovative work in the study of kidney disorders showcases the critical intersection of genetics and nephrology. Her contributions through her patents not only advance scientific understanding but also hold potential for improving patient outcomes in the realm of kidney health.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.