Company Filing History:
Years Active: 2013
Title: Michelle Becker-Hapak: Innovator in Immunology
Introduction
Michelle Becker-Hapak is a prominent inventor based in St. Louis, MO (US). She has made significant contributions to the field of immunology, particularly in the development of innovative methods for expanding antigen-specific T cell populations. Her work has the potential to advance therapeutic strategies in cancer treatment and other diseases.
Latest Patents
Michelle Becker-Hapak holds a patent for "Single chain trimers and uses therefor." This patent describes single chain trimer (SCT) molecules that comprise an MHC antigen peptide sequence, a β-microglobulin sequence, and a full-length MHC class I heavy chain sequence, all joined by linker sequences. The patent further details nucleic acids encoding these single chain trimers. The methods outlined in her patent can achieve a remarkable 10,000-100,000 fold expansion of antigen-specific CD8+ T cells within approximately 28 days, yielding over 1 billion antigen-specific CD8+ T cells from a single donor.
Career Highlights
Michelle Becker-Hapak is affiliated with Washington University, where she continues her research and development in immunology. Her innovative approaches have garnered attention in the scientific community, contributing to advancements in T cell therapies.
Collaborations
Some of her notable coworkers include Ted H. Hansen and Gerald Linette, who have collaborated with her on various research projects. Their combined expertise enhances the impact of their work in the field.
Conclusion
Michelle Becker-Hapak is a trailblazer in the realm of immunology, with her patent and research paving the way for future advancements in T cell therapies. Her contributions are vital to the ongoing efforts to improve treatment options for patients.