Company Filing History:
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1 out of 832,680 Years Active: 2002
Title: Michelle A Nelson: Innovator in Nucleic Acid Detection
Introduction
Michelle A Nelson is a prominent inventor based in Fitchburg, WI (US). She has made significant contributions to the field of nucleic acid detection, holding 2 patents that showcase her innovative approaches to biological sample analysis.
Latest Patents
Her latest patents focus on methods, compositions, and kits for detecting extremely low levels of nucleic acid, cells, and cellular material in biological samples. The nucleic acid detection systems she developed utilize either the pyrophosphorolysis reaction catalyzed by various polymerases or nuclease digestion coupled with pyrophosphorylation catalyzed by phosphoribosylpyrophosphate synthetase. This process produces either deoxyribonucleoside triphosphates or ribonucleoside triphosphates. The dNTPs are then transformed into ATP by the action of nucleoside diphosphate kinase. The ATP produced by these reactions can be detected using luciferase or NADH-based detection systems. For more sensitive detection, she has provided schemes for the amplification of NTPs and dNTPs. Additionally, her detection system for cells or cellular material in a sample involves converting AMP and a high-energy phosphate donor into ATP through the action of endogenous enzymes, followed by ATP detection.
Career Highlights
Throughout her career, Michelle has worked with notable companies, including Promega Corporation. Her work has significantly advanced the methodologies used in nucleic acid detection, contributing to various applications in biological research and diagnostics.
Collaborations
Some of her coworkers include John William Shultz and Donna M Leippe, who have collaborated with her on various projects, enhancing the impact of her inventions.
Conclusion
Michelle A Nelson is a trailblazer in the field of nucleic acid detection, with her innovative patents paving the way for advancements in biological sample analysis. Her contributions continue to influence research and diagnostic methodologies in significant ways.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.