This inventor holds 2 USPTO granted patents and 1 published patent application. Top assignees: Cayla, Invivogen. Active years: 1999-2023.
Company Filing History:
Years Active: 1999-2023
Title: Michèle Tiraby: Innovator in Immunomodulatory Compounds
Introduction
Michèle Tiraby is a prominent inventor based in Toulouse, France. He has made significant contributions to the field of immunology through his innovative patents. With a total of 2 patents, Tiraby's work focuses on developing compounds that can enhance immune responses and target specific diseases.
Latest Patents
Tiraby's latest patents include groundbreaking inventions such as "Pro-cyclic dinucleotides and pro-cyclic dinucleotide conjugates for cytokine induction." This invention provides a Pro-cyclic dinucleotide (Pro-CDN) that comprises a STING agonist cyclic dinucleotide coupled to a linker system. The Pro-CDNs can be metabolized at targeted sites into CDNs, exerting their full immunomodulatory effects. Additionally, the invention includes conjugates where a Pro-CDN is linked to a Biologically Active Molecule (BAM), which can be a cytotoxic molecule, lipid, protein, peptide, nucleic acid, sugar, or PRR ligand. The methods related to these compounds aim to treat or prevent diseases such as cancers, immunological disorders, or infections.
Another notable patent is "Suicide genes and new associations of pyrimidine nucleobase." This invention relates to suicide hybrid genes that activate pyrimidine nucleobase analogs to selectively kill transfected tumor cells or immune cells. The invention also includes eukaryotic vectors with two expression suicide gene units, enhancing the sensitization of tumor cells and HIV-infected cells in a synergistic manner.
Career Highlights
Throughout his career, Michèle Tiraby has worked with notable companies such as Invivogen and Cayla. His experience in these organizations has allowed him to develop and refine his innovative ideas in the field of immunology.
Collaborations
Tiraby has collaborated with esteemed colleagues, including Christophe Cazaux and Jean-Paul Reynes. These partnerships have contributed to the advancement of his research and the successful development of his patents.
Conclusion
Michèle Tiraby's contributions to immunology through his innovative patents demonstrate his commitment to advancing medical science. His work has the potential to significantly impact the treatment of various diseases, showcasing the importance of innovation in healthcare.