Michele Dipalo

Title: Michele Dipalo: Innovator in Microfluidic Devices and Electrogenic Cell Recording

Introduction

Michele Dipalo is a prominent inventor based in Genoa, Italy. He has made significant contributions to the fields of microfluidics and cellular electrophysiology. With a total of 2 patents, his work focuses on innovative devices and methods that enhance our understanding of cellular processes.

Latest Patents

Michele Dipalo's latest patents include groundbreaking technologies. One of his patents is for microfluidic devices and methods for using these devices. This microfluidic device features electrically conductive lower portions and upper portions designed to receive electrical signals. It also includes shielding portions that are opaque to incident optical beams, with through openings that facilitate fluid communication between compartments containing fillers and markers. The markers are designed to emit optical emissions when illuminated, allowing for advanced applications in fluid dynamics and cellular analysis.

Another notable patent is a method and device for recording intracellular action potentials in electrogenic cells. This method utilizes optoporation to create pores in cell membranes, enabling the recording of action potentials. By positioning a sample on a multi-electrode array and applying localized laser pulses, the method allows for precise recording of intracellular signals. The porous electrodes enhance the electric field, facilitating the breakdown of cell membranes and improving data acquisition.

Career Highlights

Michele Dipalo has worked with esteemed organizations such as the Fondazione Istituto Italiano Di Tecnologia and the Università Degli Studi Di Genova. His experience in these institutions has allowed him to develop and refine his innovative technologies, contributing to advancements in scientific research and applications.

Collaborations

Michele has collaborated with notable colleagues, including Francesco De Angelis and Andrea Barbaglia. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and expertise, further enhancing the impact of his work.

Conclusion

Michele Dipalo is a distinguished inventor whose work in microfluidic devices and intracellular recording methods has the potential to revolutionize scientific research. His innovative patents and collaborations highlight his commitment to advancing technology in the life sciences.