Location History:
- Zionsville, IN (US) (1986)
- Indianapolis, IN (US) (1989 - 2023)
Company Filing History:
Years Active: 1986-2023
Title: Michele C Smith: Innovator in Cancer Treatment
Introduction
Michele C Smith is a prominent inventor based in Indianapolis, IN (US). She has made significant contributions to the field of cancer treatment through her innovative research and patented inventions. With a total of 4 patents, her work focuses on combination therapies and the immobilization of biologically active molecules.
Latest Patents
One of her latest patents involves a combination therapy with Notch and PI3K/mTOR inhibitors for treating various types of cancer, including T-cell acute lymphoblastic leukemia, breast cancer, and melanoma. This patent outlines a method for using specific compounds, such as 4,4,4-trifluoro-N-[(1S)-2-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]butanamide, in conjunction with other agents to enhance treatment efficacy. Another patent focuses on the immobilization of biologically active molecules by utilizing a chelating agent that is covalently bonded to these molecules. This innovative approach allows for the effective use of transition metal ions in various applications, including affinity chromatography and assay systems.
Career Highlights
Michele has worked with notable companies such as Eli Lilly and Company and Hybritech Incorporated. Her experience in these organizations has contributed to her expertise in the pharmaceutical and biotechnology sectors.
Collaborations
Throughout her career, Michele has collaborated with esteemed colleagues, including Charles Pidgeon and Carl J Shaar. These partnerships have further enriched her research and development efforts.
Conclusion
Michele C Smith is a trailblazer in the field of cancer treatment, with a focus on innovative therapies and methodologies. Her contributions through her patents and collaborations continue to impact the medical community positively.