Company Filing History:
Years Active: 2020-2021
Title: Michael Y Sha: Innovator in Genetic Detection and Microbiology Applications
Introduction
Michael Y Sha is a prominent inventor based in Castro Valley, CA (US). He has made significant contributions to the fields of genetic detection and microbiology through his innovative inventions. With a total of 2 patents, his work focuses on enhancing the detection of genetic variations and improving laboratory processes.
Latest Patents
One of Michael Y Sha's latest patents is titled "DNA mutation detection employing enrichment of mutant polynucleotide sequences." This invention introduces a method for enriching a target polynucleotide sequence that contains genetic variations. The process involves providing two primers targeted to the sequence, using a target-specific xenonucleic acid clamp oligomer, generating multiple amplicons through PCR, and detecting these amplicons. The novel molecule, Xenonucleic Acid (XNA), selectively suppresses the amplification of DNA with wild-type alleles while amplifying DNA containing mutant alleles. This method significantly improves the clinical sensitivity for detecting actionable mutants related to lung or colorectal cancer.
Another notable patent is focused on "high resolution systems, kits, apparatus, and methods using magnetic beads for high throughput microbiology applications." This invention describes a method for transferring material between microfabricated devices using magnetic beads. The process allows for the cultivation of cells in one device and their transfer to another, enhancing the efficiency of microbiological experiments.
Career Highlights
Throughout his career, Michael Y Sha has worked with various companies, including Diacarta Ltd and General Automation Lab Technologies Inc. His experience in these organizations has contributed to his expertise in developing innovative solutions in genetic detection and microbiology.
Collaborations
Michael has collaborated with notable individuals in his field, including Michael J Powell and Aiguo Zhang. These partnerships have further enriched his research and development efforts.
Conclusion
Michael Y Sha is a distinguished inventor whose work in genetic detection and microbiology has led to significant advancements in these fields. His innovative patents demonstrate his commitment to improving healthcare and laboratory processes.