Michael Vogeser

Title: Michael Vogeser: Innovator in Mass Spectrometry and Liquid Manipulation

Introduction

Michael Vogeser is a prominent inventor based in Munich, Germany. He has made significant contributions to the fields of mass spectrometry and liquid manipulation, holding a total of 4 patents. His innovative approaches have advanced the capabilities of analytical techniques in various applications.

Latest Patents

One of Vogeser's latest patents focuses on a functional check and variance compensation in mass spectrometry. This test method checks and compensates for ion yield variances in a mass spectrometer. It involves feeding an eluate from a chromatographic separation to the spectrometer, continuously ad-mixing a separate target analyte solution at a known concentration and constant flow rate. The mixture is injected into the spectrometer, generating a detector signal for the mixture. A spectrogram is captured, which includes an integration line and a mass-spectrographic peak of the target analyte. The integration line serves as a lasting background signal underlaid to the mass-spectrometric analysis of the eluate. The evaluation of the spectrogram involves capturing an integrated mass-spectrographic peak area above the integration line and an area found under the integrated peak area of the target analyte, forming a mathematical relationship from the determined mass-spectrographic areas.

Another notable patent involves the manipulation of magnetic microparticles in a high-pressure liquid system and extraction process. This invention concerns a device and method for manipulating a liquid sample material in which magnetic microparticles are suspended. These microparticles have a functionalized surface to which an analyte is bound. The sample material is introduced into a device with a liquid system through an injection device. In the first mobile phase, the sample material is carried to an extractor, where the microparticles are immobilized by a controllable magnetic field and separated from the remaining sample material. A second mobile phase is then introduced to detach the adsorbed analyte from the surface of the microparticles, allowing for chromatographic separation and subsequent detection.

Career Highlights

Throughout his career, Michael Vogeser has worked with notable companies such as Roche Diagnostics Operations, Inc. and Tecan Trading AG. His experience in these organizations has contributed to his expertise in the field of analytical chemistry and instrumentation.

Collaborations

Vogeser has collaborated with esteemed colleagues, including Uwe Kobold and Albert Geiger. These