Michael Schwartz

Title: Michael Schwartz: Innovator in Neural Stem Cell Research

Introduction

Michael Schwartz is a prominent inventor based in Garden Grove, CA (US). He has made significant contributions to the field of neural stem cell research, holding 2 patents that focus on the isolation and characterization of neural stem cells (NSCs). His work has implications for both therapeutic applications and the understanding of various neural conditions.

Latest Patents

One of Michael Schwartz's latest patents involves the isolation of neural stem cells using gangliosides and other surface markers. During the growth and study of NSCs, a range of molecules present on the surface of multipotent neural stem and progenitor cells were identified. These markers were identified using various human and murine neural stem cell lines, including retinal stem cells. The NSC-specific markers identified included gene products as well as non-protein molecules and sugar epitopes not directly coded in the genome. Together with surface markers determined to be absent from the surface of human NSCs, these molecules provide a means to enrich for neural stem cells or neural progenitor subpopulations, particularly using combinatorial cell sorting strategies. These same molecules also represent targets for pharmacological manipulation of NSC populations and subpopulations, both in vivo and ex vivo. Furthermore, these molecules provide potential targets for therapeutic manipulation of other neural precursor-related cell types, including malignant conditions and other diseases affecting various uncommitted or replication-competent cell types.

Career Highlights

Throughout his career, Michael Schwartz has worked with notable institutions such as Children's Hospital of Orange County and The Schepens Eye Research Institute, Inc. His research has contributed to advancements in understanding neural stem cells and their potential applications in medicine.

Collaborations

Michael Schwartz has collaborated with esteemed colleagues, including Henry Klassen and Michael J Young. These collaborations have further enriched his research and expanded the impact of his work in the field of neural stem cell research.

Conclusion

Michael Schwartz is a key figure in the field of neural stem cell research, with a focus on innovative methods for isolating and characterizing these important cells. His contributions have the potential to influence therapeutic strategies for various neural conditions.