Michael S C Fung

Title: Michael S C Fung: Innovator in Complement Activation Inhibition

Introduction

Michael S C Fung is a notable inventor based in Houston, TX, recognized for his contributions to the field of complement activation inhibition. With a total of 14 patents to his name, Fung has focused primarily on developing innovative inhibitors that target crucial components involved in the complement system, showcasing significant advancements in biomedical research.

Latest Patents

Among Michael S C Fung's latest patents is the invention titled "Complement inhibitors and uses thereof." This patent discusses C2a inhibitors that bind to C2a and effectively block its functional activity in complement activation. The invention encompasses various inhibitors, including antibody molecules and their derivatives, such as immunoglobulin fragments like Fab, F(ab'), and Fv. Key among these is the monoclonal antibody designated 175-62, which has been shown to bind to C2a and inhibit its activation capability. The hybridoma producing this antibody was deposited at the American Type Culture Collection, under Accession Number PTA-1553.

Another significant patent is related to "Nucleic acids encoding antibodies that bind factor D." This invention outlines factor D inhibitors that similarly bind to factor D and prevent its functional activity during complement activation. Just like the previous patent, it features a range of inhibitors, including monoclonal antibodies such as 166-32, which block factor D's activation abilities. The hybridoma for this antibody was also deposited at the American Type Culture Collection, under Accession Number HB-12476.

Career Highlights

Throughout his career, Michael S C Fung has worked with prominent biotech companies, including Genentech, Inc. and Tanox, Inc. His innovative approaches have greatly contributed to advancements in treatment modalities targeting immune responses and inflammation.

Collaborations

Fung has collaborated with esteemed colleagues, including Cecily R Y Sun and William N C Sun. These partnerships have been pivotal in amplifying the impact of his research and developments within the scientific community.

Conclusion

Michael S C Fung’s expertise in the development of complement inhibitors marks him as an influential figure in biomedical innovation. His patented inventions continue to advance the understanding and treatment of conditions related to the immune system, emphasizing the significance of his work in the medical field.