Company Filing History:
Years Active: 2010
Title: Michael R Lerner: Innovator in Metabolic-Related Disorders
Introduction
Michael R Lerner is a notable inventor based in Rancho Santa Fe, California. He has made significant contributions to the field of metabolic-related disorders through his innovative research and patent work. His expertise in G protein-coupled receptors (GPCRs) has paved the way for potential therapeutic advancements.
Latest Patents
Michael R Lerner holds a patent titled "Human G protein-coupled receptors for metabolic-related disorders." This invention focuses on methods for identifying whether a candidate compound can modulate a GPCR, particularly those that are human and coupled to Gi, which lowers intracellular cAMP levels. The patent outlines the GPCR's role in inhibiting intracellular lipolysis and its potential as a nicotinic acid receptor. The agonists developed from this invention are aimed at treating various metabolic disorders, including dyslipidemia, atherosclerosis, coronary heart disease, stroke, insulin resistance, and type 2 diabetes.
Career Highlights
Michael R Lerner is associated with Arena Pharmaceuticals, Inc., where he continues to contribute to groundbreaking research in the pharmaceutical industry. His work has been instrumental in advancing the understanding of GPCRs and their implications in metabolic health.
Collaborations
Throughout his career, Michael has collaborated with esteemed colleagues, including David J Unett and Ruoping Chen. These partnerships have fostered a collaborative environment that enhances innovation and research outcomes.
Conclusion
Michael R Lerner's contributions to the field of metabolic-related disorders through his patent on GPCRs highlight his role as an influential inventor. His work not only advances scientific understanding but also holds promise for developing new therapeutic agents.