Company Filing History:
Years Active: 1988-1991
Title: Michael R Hollaway: Innovator in Enzymatic Detection Methods
Introduction
Michael R Hollaway is a distinguished inventor based in East Molesey, GB. He has made significant contributions to the field of enzymatic detection methods, holding 2 patents that showcase his innovative approach to analyzing various substances.
Latest Patents
Hollaway's latest patents include an enzymic method of detecting analytes and novel substrates therefor. This method utilizes a small enzymically inactive peptide fragment of an enzyme, such as ribonuclease S-peptide, which is conjugated with a complementary fragment (S-protein). This combination forms an enzyme that catalyzes a primary reaction, producing an essential coenzyme or prosthetic group for a secondary enzyme. The secondary enzyme then catalyzes a reaction that leads to a detectable result, indicating the presence of the analyte. Additionally, the patents disclose novel synthetic substrates for the primary reaction, with substrates for the ribonuclease S conjugate enzyme represented by the formula R-X, where R is a pyrimidine 3'-phosphate moiety and X is a leaving group linked to R through the 3'-phosphate group.
Career Highlights
Michael R Hollaway is currently associated with London Biotechnology Limited, where he continues to advance his research and development efforts in biotechnology. His work has positioned him as a key figure in the field of enzymatic detection.
Collaborations
Hollaway has collaborated with notable colleagues, including Brian R Rabin and Christopher J Taylorson, contributing to the advancement of innovative solutions in biotechnology.
Conclusion
Michael R Hollaway's contributions to enzymatic detection methods reflect his commitment to innovation and excellence in the field. His patents and collaborations highlight his role as a leading inventor in biotechnology.