Company Filing History:
Years Active: 2000-2001
Title: Michael Per Weber: Innovator in Heparin Derivatives
Introduction
Michael Per Weber is a notable inventor based in Kista, Sweden. He has made significant contributions to the field of medicinal chemistry, particularly in the development of heparin derivatives. With a total of 2 patents, his work has the potential to impact the treatment of various vascular disorders.
Latest Patents
Weber's latest patents include innovative heparin derivatives and processes for their preparation. One of his key inventions relates to new heparin derivatives derived from bovine or porcine heparin. These derivatives possess a molecular weight equal to or larger than standard heparin and exhibit a sulfur content that is equal to or higher than that of the starting heparin, or at least 13% w/w. They demonstrate anticoagulant activity in the anti-FXa assay of less than 10% of the standard heparin from which they were made. Additionally, these derivatives show a ratio of APTT activity over anti-FXa activity of 3-35 and a reduced prolongation of bleeding time compared to the standard heparin. Furthermore, they enhance the rate of development of coronary collaterals in dogs, equal to or better than clinically used heparin. This invention also outlines processes for the preparation of these new heparin derivatives, which can be utilized in the manufacturing of medicaments for treating ischemic heart disease and related vascular disorders.
Career Highlights
Throughout his career, Michael Per Weber has worked with prominent companies such as Pharmacia & Upjohn Aktiebolag and Pharmacia AB. His experience in these organizations has contributed to his expertise in the field of pharmaceutical innovations.
Collaborations
Weber has collaborated with notable colleagues, including Christer Jan Mattsson and Carl Magnus Svahn. Their joint efforts have further advanced the research and development of heparin derivatives.
Conclusion
Michael Per Weber's contributions to the field of heparin derivatives highlight his innovative spirit and dedication to improving medical treatments. His patents represent significant advancements in the management of vascular disorders, showcasing the importance of research and development in the pharmaceutical industry.