Michael Paul Goble

Title: Michael Paul Goble: Innovator in Pharmaceutical Chemistry

Introduction

Michael Paul Goble is a notable inventor based in San Diego, CA. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of compounds for therapeutic applications. With a total of 2 patents, Goble's work has had a meaningful impact on the treatment of various diseases.

Latest Patents

Goble's latest patents include innovative methods for preparing methanesulfonamides. One of his notable inventions is a process for preparing (S)-(−)-N-[4-[4-[ethyl(6-fluoro-6-methylheptyl)amino]-1-hydroxy]phenyl]methanesulfonamide hemifumarate salt. This process involves reacting N-[4-[(2S)-tetrahydro-5-hydroxy-2-furanyl]phenyl]methanesulfonamide with fluoroamine in the presence of triacetoxyborohydride and ethyl acetate. The result is a compound that can be converted into the hemifumarate salt. Additionally, he has developed inhibitors of hepatitis C virus RNA-dependent RNA polymerase, which are useful in therapeutic and prophylactic treatments for individuals infected with the hepatitis C virus.

Career Highlights

Throughout his career, Goble has worked with prominent companies in the pharmaceutical industry. He has been associated with Agouron Pharmaceuticals, Inc. and Pharmacia & Upjohn Company. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking research in drug development.

Collaborations

Goble has collaborated with several talented individuals in his field. Notable coworkers include Allen Borchardt and Sonja Suzanne MacKey. Their combined expertise has fostered an environment of innovation and creativity in their projects.

Conclusion

Michael Paul Goble is a distinguished inventor whose work in pharmaceutical chemistry has led to significant advancements in the treatment of diseases. His patents and collaborations reflect his commitment to innovation and improving healthcare outcomes.