Company Filing History:
1 out of 3,688 
1 out of 2 Years Active: 2025
Title: Michael Nedelcovych: Innovator in Cancer Imaging and Therapy
Introduction
Michael Nedelcovych is an accomplished inventor based in Arlington, VA (US). He has made significant contributions to the field of cancer imaging and therapy, particularly through his innovative research and patent applications. Although he currently holds no granted patents, his work has the potential to impact the medical community significantly.
Latest Patent Applications
One of Michael Nedelcovych's notable patent applications is titled "Prodrugs of 2-PMPA for Healthy Tissue Protection During PSMA-Targeted Cancer Imaging or Radiotherapy." This application discloses the use of a class of prodrugs of 2-PMPA that alter tissue distribution to non-prostate tissues. The disclosed prodrugs preferentially distribute to healthy tissues, including the kidney, lacrimal glands, and salivary glands. These areas represent sites of off-target binding and toxicity for PSMA-targeted prostate cancer imaging agents and therapies. Consequently, the 2-PMPA prodrugs can be utilized to pretreat, bind to, and shield the kidney and salivary glands from PSMA-targeted cytotoxic or radiotherapy.
Conclusion
Michael Nedelcovych's innovative work in cancer imaging and therapy showcases his dedication to advancing medical science. His research has the potential to improve patient outcomes in prostate cancer treatment.