Company Filing History:
Years Active: 2002
Title: Michael Lewis: Innovator in TGF-β Protein Purification
Introduction
Michael Lewis is an accomplished inventor based in Englewood, CO (US). He has made significant contributions to the field of biotechnology, particularly in the purification of bone-derived proteins. His innovative methods have the potential to advance research and therapeutic applications involving TGF-β proteins.
Latest Patents
Michael Lewis holds a patent for the "Isolation of purified TGF-β1 and TGF-β2 from bone tissue." This patent describes a comprehensive method for purifying bone-derived TGF-β proteins. The process includes anion exchange, cation exchange, and reverse phase HPLC processes, along with optional filtration and Heparin-Sepharose processes. The filtration process is designed to select proteins with a nominal molecular weight between approximately 10 kilodaltons and 100 kilodaltons. The anion exchange process utilizes a strongly cationic resin with quaternary amine functional groups, while the cation exchange process employs a strongly anionic resin with sulfonic acid functional groups. The TGF-β proteins can be eluted from the reverse phase HPLC column using an acetonitrile solution combined with aqueous trifluoracetic acid. These purification processes yield highly enriched TGF-β1 and TGF-β2 proteins.
Career Highlights
Michael Lewis is currently associated with Sulzer Biologics, Inc., where he continues to innovate in the field of protein purification. His work has garnered attention for its potential applications in various medical and research settings.
Collaborations
Michael has collaborated with notable colleagues, including Louis Junker and Robert Nelson. Their combined expertise contributes to the advancement of biotechnological innovations.
Conclusion
Michael Lewis is a prominent inventor whose work in the purification of TGF-β proteins is paving the way for advancements in biotechnology. His innovative methods and collaborations highlight the importance of research in this critical field.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.