Company Filing History:
Years Active: 2008-2013
Title: Michael Kotlikoff: Innovator in Nucleic Acid Technologies
Introduction
Michael Kotlikoff is a prominent inventor based in Ithaca, NY (US). He has made significant contributions to the field of molecular biology, particularly in the development of nucleic acid technologies. With a total of 2 patents, his work has the potential to impact various applications in research and medicine.
Latest Patents
Kotlikoff's latest patents include innovative technologies that enhance the functionality of nucleic acids. One of his notable inventions is related to functional nucleic acid ligands to fluorescent proteins. This invention involves a nucleic acid aptamer that binds to a fluorescent protein, forming a molecular complex. The system includes a first DNA molecule encoding the aptamer and a second DNA molecule encoding the fluorescent protein. Additionally, methods for detecting and determining the location of molecular targets using this aptamer are disclosed.
Another significant patent focuses on vectors for conditional gene inactivation. This invention provides a method for preparing gene trapping libraries and gene-targeted cells for the conditional inactivation of genes. The vector includes a mutational element cassette and a gene trap cassette, each equipped with site-specific recombination sequences.
Career Highlights
Michael Kotlikoff is associated with the Cornell Research Foundation Inc., where he continues to advance his research and innovations. His work has garnered attention in the scientific community, contributing to the understanding and application of nucleic acid technologies.
Collaborations
Throughout his career, Kotlikoff has collaborated with esteemed colleagues, including Hong-Bo Xin and John T Lis. These collaborations have further enriched his research and expanded the impact of his inventions.
Conclusion
Michael Kotlikoff is a distinguished inventor whose work in nucleic acid technologies has the potential to revolutionize various fields. His patents reflect a commitment to innovation and scientific advancement.