Rockville, MD, United States of America

Michael Kaleko

This inventor holds 63 USPTO granted patents and 19 published patent applications, plus 6 CIPO patents and 14 EPO patents, primarily in Alkaline Phosphatase (CPC class A61K). Top assignees: Synthetic Biologics, Inc., Novartis Ag, Theriva Biologics, Inc.. Active years: 1999-2026.

USPTO Granted Patents = 63 

% Patents Active = 82.5

 

 

Average Co-Inventor Count = 2.8

ph-index = 7

Forward Citations = 216(Granted Patents)

Forward Citations (Not Self Cited) = 169(Dec 10, 2025)


Inventors with similar research interests:


Location History:

  • Potomac, MD (US) (2006 - 2012)
  • Rockville, MD (US) (1999 - 2024)

Company Filing History:


Years Active: 1999-2026

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Areas of Expertise:
Alkaline Phosphatase
Beta-Lactamase
Microbiome Protection
Oncology Treatments
Radiation Disorders
Neurodevelopmental Disorders
Carbapenemases
Oral Antibiotics
Formulations
Therapy
Improved Properties
Complement Factor B
63 patents (USPTO):Explore Patents

Title: Michael Kaleko: A Pioneer in Patent Innovations

Introduction

Michael Kaleko is an accomplished inventor based in Rockville, MD, with an impressive portfolio of 57 patents. His work focuses on innovative formulations that address critical therapeutic needs, particularly in the field of biotechnology and pharmaceuticals.

Latest Patents

Among his recent inventions are two groundbreaking patents. The first, titled "Beta-lactamase formulations and uses thereof," highlights the development of modified-release formulations containing beta-lactamase, designed to deliver substantial amounts of the enzyme in the intestines for therapeutic applications. The second patent, "Alkaline phosphatase formulations," outlines similar innovative modified-release powder formulations comprising an alkaline phosphatase-based agent, which also targets intestinal release for therapeutic benefits.

Career Highlights

Kaleko has made significant contributions through his roles at leading companies such as Synthetic Biologics, Inc. and Novartis AG. His tenure at these organizations has allowed him to develop and refine his expertise in creating novel medical formulations that meet pressing health challenges.

Collaborations

Throughout his career, Michael Kaleko has had the opportunity to collaborate with talented individuals like Sheila Connelly and Tianci Luo. These partnerships have been instrumental in advancing his research and patent innovations in the field.

Conclusion

Michael Kaleko's dedication to innovation in biopharmaceutical formulations is evident through his numerous patents and collaborative efforts. As a leading inventor, he continues to make a remarkable impact in the field, contributing to advancements that enhance therapeutic outcomes for patients.

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