Michael K Tanner

Title: Michael K Tanner: Innovator in Immunoregulation

Introduction

Michael K Tanner is a notable inventor based in Crestwood, KY (US). He has made significant contributions to the field of immunoregulation and immunotherapy. His innovative work focuses on the mechanisms that inhibit lymphocyte proliferation, which is crucial for advancing therapeutic strategies in immunology.

Latest Patents

Michael K Tanner holds a patent titled "Method of using Zot to inhibit lymphocyte proliferation in an antigen-specific manner." This patent describes methods of using Zot or zonulin as an antigen-specific inhibitor of antigen presenting cell (APC) activity and lymphocyte proliferation. The invention is primarily useful in the field of immunoregulation and immunotherapy. Specifically, Zot and zonulin inhibit APC-mediated antigen-specific lymphocyte proliferation in a dose-dependent manner. This effect is associated with the presence of a macrophage surface receptor to which Zot binds in a specific and saturable way. The down-regulation of the immune response is, at least in part, associated with a decreased uptake of antigen. Michael K Tanner has 1 patent to his name.

Career Highlights

Michael K Tanner is affiliated with the University System of Maryland, where he continues to contribute to research and innovation in immunology. His work has implications for developing new therapies that can modulate immune responses effectively.

Collaborations

Michael has collaborated with esteemed colleagues such as Alessio Fasano and Marcelo B Sztein. Their combined expertise enhances the research efforts in the field of immunoregulation.

Conclusion

Michael K Tanner's innovative work in immunoregulation and his patent on the use of Zot highlight his contributions to advancing therapeutic strategies in immunology. His research continues to pave the way for new approaches in immunotherapy.